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#1

Loop Extrusion Reversal by Condensin Motor is Mediated by Catch Bonds

Atreya Dey, Guang Shi, Ryota Takaki et al. 2026-05-06

Structural Maintenance Complexes (SMC) are energy consuming motors that are important in folding the genome by loop extrusion (LE) in all stages of the cell cycle. Single molecule magnetic tweezer pulling experiments have revealed that condensin, a member of the SMC family involved in mitosis, takes

#4

A framework for modeling and inferring tracer diffusion in crowded environments

Jinseok Lee, Tong Lin, Mengyang Gu et al. 2026-05-05

Tracer diffusion in crowded environments is central to many biological and soft matter systems, but quantitative frameworks for linking tracer motion to environmental structure remain limited. Here, we study the transport of rigid tracers in suspensions of soft particles and within living cells. Exp

#5

Predicting and controlling nonlinear neuro-mechanical locomotion dynamics

Alexander E. Cohen, Jörn Dunkel 2026-05-05

Neuromechanics aims to understand the link between an animal's neural activity and its physical behaviors. Recent advances in experimental and machine learning techniques enable simultaneous recordings of neural and locomotion dynamics over long time periods and across multiple behavioral transition

#6

The Incommensurability Principle in Biological Transport

Riccardo Marchesi 2026-05-04

Biological vascular networks exhibit branching exponents ($α^* \approx 2.72$) conserved across developmental stages and observed in multiple mammalian species [Kassab et al. (1993), Zamir (1999)], despite vast metabolic and anatomical variation. We prove this universality is a mathematical necessity

#7

Optimal information transmission in a sequential model for cell division

Krishna P. Ramachandran, Motasem ElGamel, Farshid Jafarpour et al. 2026-05-04

In proliferating cell populations, adaptive changes to biochemical reactions can change a cell's division time, which in turn can change the population size. However, biochemical reactions are subject to noise, and therefore the conditions for optimal information transmission from the molecular to t